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Aseptic stainless steel fermentation tank production demand

Data: 2020-12-11


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Aseptic stainless steel fermentation tank production demand

Aseptic stainless steel fermentation tanks belong to a sterile working environment. The biological strains are independent and directional. An excellent stainless steel fermentation tank should prevent the derivation of bacteria and phages from the production of the tank to the production process to ensure the fermentation process. The smooth and efficient.

Stainless Steel 316L bioreactor

  • Material requirements for stainless steel fermentation tanks:

The materials often used are 316L, 304L, 304, 916; the inner surface of the fermenter should be smooth and free of dead corners, to prevent material accumulation, and easy to clean and sterilize after the fermentation; and the culture medium (including the feed material), the fermentation broth ( The materials in contact with microorganisms, bacteria, vaccines, cells, etc. must be made of materials that are non-toxic, corrosion-resistant, do not absorb or chemically react with the above-mentioned substances.

  • The requirements of stainless steel fermentation tanks for internal and external environments:

Bio-fermentation tanks involve active substances in the cultivation process, so they must comply with bio-safety standards. It must not only prevent the contamination of external microorganisms, but also prevent the cultured substances in the fermentation tank from polluting the surrounding environment. 

Therefore, the biological fermentation tank should be a system device with good sealing performance, and its emptying and discharging the gas and liquid in the tank need to be filtered to remove active substances;

  • The stainless steel biological fermentation tank should have excellent mass transfer/heat transfer effects:

Excellent material mixing performance, so as to provide the best growth temperature of the culture. When carrying out animal cell culture, in addition to mixing well, animal cells must not be broken to ensure the smooth progress of the biological fermentation culture process.

316L Stainless Steel bioreactor

  • Three key points of the core design of stainless steel fermentation tank:

1. Installation and disassembly
2. Convenient cleaning and sterilization, operation and maintenance
3. Stainless steel fermentation tanks withstand high pressure steam sterilization

The design specifications of stainless steel fermentation tanks are 10L, 100L, 1000L and other specifications, which need to be designed and selected according to the process.